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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCH2 All Species: 6.36
Human Site: T993 Identified Species: 14
UniProt: O75038 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75038 NP_055453.2 1416 154668 T993 R D T R P L S T Q R P L P P L
Chimpanzee Pan troglodytes XP_001149239 1685 188441 A972 V D R N L L G A L S L P V S E
Rhesus Macaque Macaca mulatta XP_001085424 1423 155915 T1000 R D T R P L S T Q R P L P P P
Dog Lupus familis XP_546733 1387 151432 M977 R D T R P F S M Q R T G S S L
Cat Felis silvestris
Mouse Mus musculus A2AP18 1501 164279 L1074 R D T R L F P L Q R P I S P L
Rat Rattus norvegicus Q62688 1096 122754 S706 S I M R D E V S Y F S A N T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q2VRL0 637 72514 V247 A A S D Y P V V L S L E N H C
Frog Xenopus laevis Q32NH8 758 87399 D368 K D V I S A I D K Y A F R V S
Zebra Danio Brachydanio rerio A5D6R3 784 89362 A394 I E T I A Q Y A F K A S P Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25455 1318 146373 S928 P V E S L A T S P K H R P S I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783611 2724 302530 D1213 T L S R I L D D D D L V F P M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.4 94 78.7 N.A. 77.2 21.2 N.A. N.A. 21.2 24.7 24.5 N.A. 24.2 N.A. N.A. 26.4
Protein Similarity: 100 59.9 95.4 82.9 N.A. 81.6 36.7 N.A. N.A. 30.7 35.3 35 N.A. 40.3 N.A. N.A. 35.7
P-Site Identity: 100 13.3 93.3 60 N.A. 60 6.6 N.A. N.A. 0 6.6 13.3 N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 13.3 93.3 60 N.A. 66.6 13.3 N.A. N.A. 6.6 20 26.6 N.A. 33.3 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 10 19 0 19 0 0 19 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 55 0 10 10 0 10 19 10 10 0 0 0 0 0 % D
% Glu: 0 10 10 0 0 10 0 0 0 0 0 10 0 0 10 % E
% Phe: 0 0 0 0 0 19 0 0 10 10 0 10 10 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % H
% Ile: 10 10 0 19 10 0 10 0 0 0 0 10 0 0 10 % I
% Lys: 10 0 0 0 0 0 0 0 10 19 0 0 0 0 10 % K
% Leu: 0 10 0 0 28 37 0 10 19 0 28 19 0 0 28 % L
% Met: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 19 0 0 % N
% Pro: 10 0 0 0 28 10 10 0 10 0 28 10 37 37 19 % P
% Gln: 0 0 0 0 0 10 0 0 37 0 0 0 0 0 0 % Q
% Arg: 37 0 10 55 0 0 0 0 0 37 0 10 10 0 0 % R
% Ser: 10 0 19 10 10 0 28 19 0 19 10 10 19 28 10 % S
% Thr: 10 0 46 0 0 0 10 19 0 0 10 0 0 10 0 % T
% Val: 10 10 10 0 0 0 19 10 0 0 0 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 0 10 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _